Current Study Opportunities at CRC

Studies at CRC change frequently.  For the most up to date information of current enrolling studies please E-mail Us or call 314-514-8509 to see if you qualify for a study.

 Now Enrolling for the Following Studies at CRC 

                                        

Study #1 – Participants Needed who Have Been Using a Daily Asthma Maintenance Inhaler for the Past 3 Months

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Study #2 – Asthma Patients Needed who Have Been Using a Combination Corticosteriod Inhaler Daily for the Past 4 Weeks 

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Study #3 – Looking for Participants Who Are Currently Treating Their Asthma with Daily Medication or a Rescue Inhaler

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Study #4 – Participants Needed who are Using Oral Steroids Daily to Treat Their Asthma

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Study #5 – Participants Needed who have had 2 or More Asthma Exacerbations in the Past Year that Required Oral Steroids and/or Hospitalization 

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Study #6- Looking for Mild Asthmatics to evaluate a Bioequivalent (Generic) Asthma Medication 

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Study #7- Mild to Moderate Asthmatics using a rescue inhaler a couple times a week but not daily 

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Study #8- Moderate to Severe Asthmatics on low to medium dose inhaled steroids or using a rescue inhaler

 


Study #1    Have you been using a daily maintenance inhaler for the past 3 months?

The Clinical Research Center is conducting a research study to evaluate the safety and effectiveness of an investigational medication for asthma.  The study consists of 5 visits over approximately 12 weeks. The study is placebo controlled.

To Qualify:

  • You must be 18-75 years of age 
  • You must be on inhaled corticosteriods consistently for at least 3 months prior to starting the study
  • You must be experiencing symptoms despite current treatment
  • You must have a diagnosis of Asthma for at least one year
  • You must not have a diagnosis of any other significant respiratory disease
  • You must not be a current or former smoker with a pack year history more than 10

For more information, please call Monica at 314-514-8509 or fill out the form on the right.

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Study #2    Have you been using a daily combination inhaler for the past 4 weeks to treat your asthma?

The Clinical Research Center is conducting a research study to evaluate the safety and efficacy of an investigational medication to treat asthma.  The study consists of 10 visits over approximately 7 months. You will stay on your current asthma medications, and the study drug will be added onto you daily standard of care.

To Qualify:

  • You must be 12-80 years of age
  • You must have a diagnosis of Asthma
  • You must be using inhaled corticosteriods in combination with long acting beta-agonists for asthma for at least 4 weeks prior to starting the study
  • You must not have a history of life-threatening asthma, such as intubation or respiratory arrest
  • Your body mass index must be under 40
  • You must not have a diagnosis of any other significant respiratory disease
  • You must not be a current or former smoker with a pack year history more than 10

For more information, please call Monica at 314-514-8509 or fill out the form on the right.

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Study #3    Are you currently treating your asthma with either a daily maintenance medication or a rescue inhaler?

The Clinical Research Center in West St. Louis County is evaluating the effectiveness of an investigational inhaler for asthma. The study consist of 3 visits over approximately 8 weeks and is placebo-controlled.

To Qualify:

  • You must be 12 years of age or older
  • You must have persistent asthma for at least 12 weeks prior to starting the study
  • You must not have sleep apnea that requires the use of a C-pap or Bi-pap machine
  • You must be using a daily maintenance inhaler at a stable dose
  • You cannot have a history of life-threatening asthma, including intubation
  • You cannot be a current smoker or a former smoker with a pack year history greater than 10

For more information, please call Monica at 314-514-8509 or fill out the form on the right.


 

Study #4     Have you been using oral steroids every day for the past 6 months to treat your asthma?

The Clinical Research Center is conducting a research study to evaluate the safety and effectiveness of an investigational medication for asthma. The study will be added onto your current asthma medications and will be given by  monthly injections.  The study will consist of 20 visits over the course of 72 weeks.

To Qualify:

  • Participants must be between the ages of 18-80
  • Participants must have a diagnosis of asthma for at least 12 months and cannot have any other respiratory condition
  • Participants must be using 7.5mg to 30mg of oral steroids daily for the past 6 months and the dose must be stable for 30 days prior starting the study
  • In addition to daily oral steroids, participants must be using physician-prescribed medium to high dose inhaled corticosteroids for the past 12 months
  • Participants must have a history of at least 1 asthma exacerbation within 12 months, this includes a burst of systemic corticosteroids for at least 3 days, inpatient hospitalization for at least 24 hours, or an ER visit that required treatment with systemic corticosteroids
  • Participants must not be a current or former smoker with a smoking history of greater than 10 pack years

For more information, please call Monica at 314-514-8509 or fill out the form on the right.

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Study #5    Have you had 2 or more asthma exacerbations in the last year that required oral steroids and/or hospitalization?

The Clinical Research Center is conducting a research study to evaluate the safety and effectiveness of an investigational medication for asthma. The study medication will be added onto your current asthma medications and will be given by  monthly injections.  The study will consist of 19 visits over the course of 68 weeks.

To Qualify:

  • Participants must be between the ages of 12-80
  • Participants must have a diagnosis of asthma for at least 12 months and cannot have a diagnosis of any other respiratory condition
  • Participants must be using physician-prescribed medium to high dose inhaled corticosteriods for the past 12 months and 2 daily controller medication either seperately or in combination at a stable dose for 3 months prior starting the study
  • Participants must have a history of at least 2 asthma exacerbations within the past 12 months, that include either a burst of systemic corticosteroids for at least 3 days, inpatient hospitalization for at least 24 hours, or an ER visit that required treatment with systemic corticosteroids
  • Participants must not be a current or former smoker with a smoking history of greater than 10 pack years

For more information, please call Monica at 314-514-8509 or fill out the form on the right.

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Study #6     Have you been diagnosed with mild asthma and are interested in evaluating an investigational medication for asthma?

The Clinical Research Center in West St. Louis County is evaluating the effectiveness of an bioequivalent (generic) inhaler for asthma. The study consist of 5 visits that can be completed in as little as 2 weeks and is placebo-controlled. A methacholine challenge will be performed at each visit.

To Qualify:

  • You must be 18 – 65 years of age 
  • You must have a clinical history of stable, mild asthma for at least 6 months
  • You cannot have a gone to the ER or have been hospitalized for acute asthma symptoms in the past 3 months
  • You cannot be a current smoker or a former smoker with a pack year history greater than 5 years
  • You cannot have uncontrolled diabetes or hypertension
  • You cannot have a history of seasonal asthma flares during the current season

For more information, please call Monica at 314-514-8509 or fill out the form on the right.

Study #7     Have you been diagnosed with asthma and are interested in evaluating an investigational medication for asthma?

The Clinical Research Center in West St. Louis County is evaluating the effectiveness of an bioequivalent (generic) inhaler for asthma. The study consist of 5 visits and the duration of the study is approximately 8 weeks. 

To Qualify:

  • You must be 18 years of age of age or older
  • You must have a clinical history of asthma for at least 6 months
  • You cannot be a current smoker or a former smoker with a pack year history greater than 5 years
  • You cannot have uncontrolled diabetes or hypertensionFor more information, please call Monica at 314-514-8509 or fill out the form on the right.

Study #8     Do you have moderate to severe Asthma defined by treating it with low to medium doses of inhaled steroids or simply a rescue inhaler?

The Clinical Research Center in West St. Louis County is evaluating the effectiveness of an bioequivalent (generic) inhaler for asthma. The study consist of 7 visits that can be completed in approximately 8 weeks. 

To Qualify:

  • You must be 18 – 65 years of age 
  • You must have a clinical history of moderate to severe asthma for at least 6 months
  • You cannot be a current smoker or a former smoker with a pack year history greater than 5 years
  • You cannot have uncontrolled diabetes or hypertension

For more information, please call Monica at 314-514-8509 or fill out the form on the right

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