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Current Studies

 The Clinical Research Center conducts research studies in the areas of Asthma, Allergy and COPD.  We frequently update this page with our current study information so check back often.

  Please e-mail Becky or Monica at This email address is being protected from spambots. You need JavaScript enabled to view it. or call 314-514-8509 to see if you qualify for a study. 

 

 

1.Have You Been Using a Low to Medium Dose Inhaled Steriod for the Past 3 Months?  

2. Are You Interested in Evaluating an Investigational Medication for COPD?

3.Do You Have Nasal Polyps and Struggle to Control Your Symptoms Despite Treatment? 

4. Are You Currently Treating your COPD with a Daily Medication?

5. Are You Currently Treating Your Asthma with Daily Medication or Rescue Medication?

 

 

 

 

 You can also sign-up for our monthly newsletter that contains information on current St. Louis Research Studies at CRC and additional updates in the world of Asthma, Allergy and COPD.

 

1. Have you been using a low to medium dose inhaled steriod for the past 3 months?

The Clinical Research Center is conducting a research study to evaluate the safety and efficacy of an investigational medication to treat asthma.  The study consists of 9-10 visits over 16-18 weeks. You will use both an inhaler and nebulizer during the course of this study.

To Qualify:

  • You must be 18-75 years of age
  • You must have a diagnosis of Asthma for at least 1 year
  • You must not have a history of life-threatening asthma or any other significant respiratory disease
  • You cannot have undergone major surgery in the past 3 months
  • You cannot have used immunosuppresvive therapy, oral or injected steriods, or any monoclonal antibodies in the past 12 weeks
  • You must not be a current or former smoker with a pack year history more than 10

 

2. Are you interested in evalutating an investigational medication for COPD?

 The Clinical Research Center is conducting a placebo controlled study to evaluate an investigational medication for COPD.  The study medication is a bio-equivalent medication to Spiriva.  Your participation in the study could last up to 26 weeks and consist of up to 8 visits.

To Qualify:

  • You must be over the age of 40
  • You must be using albuterol only to treat your COPD or be willing to change your current COPD medications for the duration of the study
  • You must be a current or former smoker with a pack year history of at least 10 years
  • You must not use oxygen for more than 12hrs a day
  • You must not have irregular day/night, waking/sleeping cycles, i.e. night shift workers 

 

 3. Do you have nasal polyps and struggle to control your symptoms despite treatment?

The Clinical Research Center is conducting a research study to evaluate the safety and effectiveness of Omalizumab (Xolair) compared with placebo for the treatment of chronic nasal polyps.  The study consists of 10-14 visits over approximately 52 weeks. The medication is delivered by injection.

To Qualify:

  • You must be between the ages of 18 to 75
  • You must have moderate to severe nasal polyps on both sides of your nose
  • You must be using inhaled nasal steriods to treat your nasal polyps for at least 4 weeks prior to starting the study
  • You must not be allergic or have a hypersensitivity to Omalizumab
  • You must be experiencing significant symptoms, such as chronic congestion or loss of smell
  • You cannot have undergone nasal surgery within the past 6 months

 

4. Are you currently treating your COPD with a daily medication?

The Clinical Research Center is conducting a clinical trial to evaluate a investigational COPD medication.  The study consists of 5-7 visits over approximately 10 weeks.  The study does include a placebo arm.

To Qualify:

  • You must be 40 years of age or older
  • You must have a diagnosis of COPD for at least a year
  • You must currently be treating your COPD with a daily medication for at least 8 weeks prior to starting the study 
  • You must be a current or former smoker with at least a 10 pack year history

  

 

5. Are you currently treating your asthma with either a daily maintenance medication or a rescue inhaler?

The Clinical Research Center in West St. Louis County is evaluating the effectiveness of an investigational inhaler versus Symbicort 80/4.5.  The study is placebo-controlled. The study consists of 3-4 office visits over approximately 8-10 weeks.

To Qualify:

  • You Must be 18 years of age or older
  • You Must be diagnosed with asthma for at least six months
  • You Must be using a daily maintenance inhaler at a stable dose for the past 4 weeks or using a rescue inhaler as needed
  • You cannot have a history of life-theatening asthma, including intubation or seizures due to lack of oxygen
  • You cannot have visited the ER or Urgent Care for your asthma or have been hospitalized for asthma in the past year
  • You cannot be a current smoker or a former smoker with a pack year history greater than 10